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N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine
| Product Name | N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine |
| Product Code | N00008982 |
| Chemical name | N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine |
| Synonyms | GS 7160 |
| Impurity | |
| CAS Number | 376633-24-8 |
| Alternate CAS # | |
| Molecular form | C₁₂H₁₉N₆O₅P |
| Appearance | |
| Melting Point | |
| Mol. Weight | 358.29 |
| Storage | |
| Solubility | |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine is a metabolite of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral. |
| Dangerous Goods Info | |
| References | Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007); |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 376633-24-8 | Purchase 376633-24-8 | Order 376633-24-8 | 376633-24-8 supplier | 376633-24-8 manufacturer | 376633-24-8 distributor | 376633-24-8 cost |
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